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PerkinElmer® Operetta™

High Content Screening Systems PerkinElmer® Operetta™

As scientists try to answer increasingly complex biological questions, they need to conduct imaging experiments on a larger scale. But analyzing samples manually can be a long and difficult process , increasing the chance of producing biased data. That’s why more scientific researchers are turning to high throughput biology, where automation meets cellular biology. And why they rely on the Operetta® High Content Imaging System, the superior solution for delivering it.

Stunning image quality

  • High numerical aperture objectives give exceptional images for higher quality data and reliable results
  • Fast widefield imaging for routine applications
  • Confocal imaging option for image quality without compromise for more reliable data in 2D and 3D. Use confocal imaging to eliminate background, improve signal-to-noise and to protect live cell samples by minimizing photobleaching and phototoxicity
  • Unsupervised automated image acquisition and autofocus for reliable high content imaging from slides to multiple plates
  • Low and high magnification plus a large field of view allows you to look at the whole well and choose an area of interest for detailed analysis
  • Compatible with our range of imaging microplates for the best quality images
  • Expert, global service and applications support from our dedicated team of lab- and field-based application specialists, plus an exclusive HCS support portal

Software in harmony with your research goals

  • Easy to set up assays, automate experiments, analyze data and store, retrieve and present results, making it ideal for the multi-user, multi-departmental environment
  • Intuitive Harmony® High Content Imaging and Analysis Software makes it easy for biologists to turn their biology into unbiased quantitative data
  • NEW! Intuitive plate wizard for even easier set up of new plate types - automatically detects the important parameters plate bottom height and plate bottom thickness.
  • Ready-made solutions for a range of common applications enable new users to get started with high content image analysis right away using the pre-configured sequences
  • User-configurable image analysis building blocks for easy creation of customized high content analysis applications
  • NEW! STAR analysis provides a more detailed analysis of cellular morphology to accurately differentiate cellular phenotypes with parameters that describe cellular symmetry and compactness as well as the intracellular distribution of fluorescence
  • Texture analysis for applications where intensity and morphology are not suitable or do not deliver robust readout and reproducible results giving you a more complete picture of your biology
  • Transfer and view data from any computer that has Harmony High Content Imaging and Analysis Software
  • NEW & IMPROVED! PhenoLOGIC™ machine learning option enables you to teach the software to create optimized algorithms for your experiment, segmentation and cell classification easier

Flexibility and ease for all your applications

  • Suitable for a wide range of fixed and live cell applications - view our Operetta application notes and see for yourself
  • Live cell chamber option to maintain environmental conditions (temperature, CO2) to protect your live cell samples
  • Kinetic capabilities for carrying out time course experiments for a better understanding of cellular dynamics
  • Integrates with our robotic automation platforms for a fully automated solution enables you to teach the software to create optimized algorithms for your experiment, making tailored image analysis easier


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